![]() ![]() Wednesday, your internal clock still thinks it's 1 a.m. ![]() Jet lag occurs because crossing multiple time zones puts your internal clock (circadian rhythms), which regulates your sleep-wake cycle, out of sync with the time in your new locale.įor example, if you leave New York on a flight at 4 p.m. Jet lag can occur anytime you cross two or more time zones. ![]() Request an Appointment at Mayo Clinic Causes A disruption to your circadian rhythms
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